Fernando Ayllon

Curriculum Vitae
Earlier in my career, I focused on how individual variation gets ramped up to population dynamics and to evolutionary processes. Does individual variation matter or does it get averaged out once it gets scaled up to population levels or to evolutionary timescales? What is the relationship between variation and adaptation? The role of selection in the reproductive isolation of natural populations has been widely debated and some studies suggest that this evolutionary force can produce the kind of isolation that separates species in the wild. Most of my research activity was focused on the evolution in natural populations of salmonids and the exploration of the evolutionary and genetic processes that shape population structure and speciation of the Salmo genus. Generated knowledge greatly impacted broodstock management at the species southern limit distribution range.
Modern Population Genetics connected me experimentally to Molecular Genetics allowing me to investigate polymorphisms distribution at a molecular level. With the last advances in Genomics my present research interest has directed towards understanding the molecular mechanisms underlying the maintenance and adaptive value of polymorphisms and its applications to the farming industry. My work at the University of Turku (Finland) focused on whole genome methylation patterns in sex chromosomes. The understanding on epigenetic processes that modulate gen dose and sex-specific gene expression will benefit further research lines involving triploid production or sterility genes in salmon. Later on, my work at The Institute of Marine Research - IMR (Norway) unravelled the genetic basis behind age at maturity in Atlantic salmon, generating the basis for several follow-up projects in my current research group. Likewise, the developed and implemented bioinformatic and statistical tools have set a standard for the group’s future publications. I also anticipate that these findings will impact the salmon farming industry by reducing the losses generated by early puberty in salmon.
Stepping up in the functional implications of the genetic variability, I am also involved in the implementation of state of the art gene editing technologies in order to elucidate the function of relevant genes. We are currently using CRISPR-Cas9 technology to induce genetic modifications through homology-directed repair in salmon embryos. This will improve the frequency of precise gene modifications and extent our knowledge in the function of genes related to aquaculture relevant traits. Other relevant projects I take part on include the production of Atlantic salmon double haploid males and the genetics basis of carotenoids metabolism that will ultimately benefit fish farming industry.
I gather a strong background in modern Genetics coming from almost twenty years experience in the fields of Cell Biology, Molecular Genetics, Genomics, Heavy-duty Bioinformatics as well as RNA and Gene expression studies. All my research has been published in peer reviewed international journals within the first quartile of multidisciplinary fields. I also have a proven expertise in multidisciplinary international projects as well as in continued collaboration with a wide variety of international researchers. Since I arrive to IMR, my multidisciplinary background, international profile and communication skills have served as pivot for collaboration not only with other scientists from my research group, but also with different groups and institutions.
Modern Population Genetics connected me experimentally to Molecular Genetics allowing me to investigate polymorphisms distribution at a molecular level. With the last advances in Genomics my present research interest has directed towards understanding the molecular mechanisms underlying the maintenance and adaptive value of polymorphisms and its applications to the farming industry. My work at the University of Turku (Finland) focused on whole genome methylation patterns in sex chromosomes. The understanding on epigenetic processes that modulate gen dose and sex-specific gene expression will benefit further research lines involving triploid production or sterility genes in salmon. Later on, my work at The Institute of Marine Research - IMR (Norway) unravelled the genetic basis behind age at maturity in Atlantic salmon, generating the basis for several follow-up projects in my current research group. Likewise, the developed and implemented bioinformatic and statistical tools have set a standard for the group’s future publications. I also anticipate that these findings will impact the salmon farming industry by reducing the losses generated by early puberty in salmon.
Stepping up in the functional implications of the genetic variability, I am also involved in the implementation of state of the art gene editing technologies in order to elucidate the function of relevant genes. We are currently using CRISPR-Cas9 technology to induce genetic modifications through homology-directed repair in salmon embryos. This will improve the frequency of precise gene modifications and extent our knowledge in the function of genes related to aquaculture relevant traits. Other relevant projects I take part on include the production of Atlantic salmon double haploid males and the genetics basis of carotenoids metabolism that will ultimately benefit fish farming industry.
I gather a strong background in modern Genetics coming from almost twenty years experience in the fields of Cell Biology, Molecular Genetics, Genomics, Heavy-duty Bioinformatics as well as RNA and Gene expression studies. All my research has been published in peer reviewed international journals within the first quartile of multidisciplinary fields. I also have a proven expertise in multidisciplinary international projects as well as in continued collaboration with a wide variety of international researchers. Since I arrive to IMR, my multidisciplinary background, international profile and communication skills have served as pivot for collaboration not only with other scientists from my research group, but also with different groups and institutions.
Publikasjoner
Faglige foredrag
2016
Genome resequencing of geographically distinct Atlantic Salmon (Salmo salar) populations reveals adaptive divergence
2016
Adaptive plasticity in Atlantic salmon- genetic predisposition of time at maturity and environmental triggers
Vitenskapelige artikler (NVI)
2018
Investigating the frequency of triploid Atlantic salmon in wild Norwegian and Russian populations
BMC Genetics
19:90
p. 1-9
2018
Vgll3 and the Hippo pathway are regulated in Sertoli cells upon entry and during puberty in Atlantic salmon testis
Scientific Reports
8:1912
p. 1-11
2016
Atlantic salmon populations reveal adaptive divergence of immune related genes - A duplicated genome under selection
BMC Genomics
17:610
p. 1-12
2015
The vgll3 Locus Controls Age at Maturity in Wild and Domesticated Atlantic Salmon(Salmo salar L.) Males
PLoS Genetics
11:e1005628
2011
Impact of habitat fragmentation on the genetics of populations in dendritic landscapes
Freshwater Biology
56
p. 2567-2579
2011
Impact of climate change and human-mediated introgression on southern European Atlantic salmon populations
Global Change Biology
17
p. 1778-1787
2011
Interspecific Hybridization, a Matter of Pioneering? Insights from Atlantic Salmon and Brown Trout.
Journal of Heredity
102
p. 237- 242
2010
Not all lineages are equally invasive: Genetic origin and life-history in salmonids acclimated to the Southern Hemisphere
Biological Invasions
12
p. 3485-3495
2008
Interspecific hybridization and introgression are associated with stock transfers in salmonids
Aquaculture
278
p. 31-36
2007
Introgression in the genus Salmo via allotriploids
Molecular Ecology
16
p. 1741-1748
2006
Rapid evolution of brown trout acclimated in virgin Subantarctic ecosystems
Journal of Evolutionary Biology
19
p. 1352-1358
2006
Genetic history of the population of Atlantic salmon, Salmo salar L., under restoration in the Connecticut River, USA
ICES Journal of Marine Sciences
63
p. 1269-1273
2006
Loss of regional population structure in Atlantic salmon, Salmo salar L., following stocking
ICES Journal of Marine Sciences
63
p. 1286-1289
2006
Maintenance of a small anadromous subpopulation of brown trout (Salmo trutta L.) by straying
Freshwater Biology
51
p. 351-358
2006
Stock transfers in Spanish Brown trout populations: A long-term assessment
Environmental Biology of Fishes
75
p. 153- 157
2004
Bottlenecks and genetic changes in Atlantic salmon stocks introduced in the Subantarctic Kerguelen Islands
Aquaculture
237
p. 103-116
2004
Asymmetry of post-F1 interspecific barriers in salmonids
Aquaculture
234
p. 77-84
2004
Interspecific hybridization between Atlantic salmon and brown trout introduced in the Subantarctic Kerguelen Islands
Aquaculture
230
p. 81-88
2003
Micronucleus Test in Freshwater Fish Species. An Evaluation of its Sensitivity for Application in Field Surveys
Ecotoxicology and Environmental Safety
56
p. 442-448
2003
Reproduction of interspecific hybrids of Atlantic salmon and brown trout in a stream environment
Freshwater Biology
48
p. 1100- 1104
2003
Assessing pollution in coastal ecosystems: a preliminary survey using the micronucleus test in the mussel Mytilus edulis
Ecotoxicology and Environmental Safety
55
p. 24-29
2001
Induction of micronuclei in eel (Anguilla anguilla L.) by heavy metals
Ecotoxicology and Environmental Safety
49
p. 139-143
2001
Micronuclei and other nuclear lesions as genotoxicity indicators in rainbow trout Oncorhynchus mykiss
Ecotoxicology and Environmental Safety
49
p. 221-225
2000
Conventional armament wastes induce micronuclei in wild brown trout Salmo trutta
Mutation Research
70
p. 169-176
2000
Induction of micronuclei and other nuclear abnormalities in European minnow Phoxinus phoxinus and mollie Poecilia latipinna: an assessment of the fish micronucleus test
Mutation Research
467
p. 177-186
1998
Baby´s Formula Feeding Labeling Analysis: Macronutrient Ratio Study
Nutrición Clínica (peer reviewed - Spanish)
XVI/215 #6
p. 19-27
Annet tidsskriftbidrag
American Fisheries Society Annual Meeting (Peer reviewed congress contribution)
Changes in genetic diversity following enhancement of wild populations at the southern limit of Atlantic salmon distribution
American Fisheries Society Annual Meeting
133
p. 118
Oversettelsesarbeider
2008
Genética - Novena edición (Introduction to Genetics Analysis 9th Edition)
McGraw- Hill/Interamericana de España, S.A.U. ISBN 978-84-481-6091-3
Poster
2018
VGLL3 AND THE HIPPO PATHWAY ARE REGULATED IN SERTOLI CELLS UPON ENTRY AND DURING PUBERTY IN ATLANTIC SALMON TESTIS.
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