Marianne Hauglid Flågeng

Senioringeniør
Telefon: 99603177
Avdeling: Kjemi- og fremmedstoff lab

Publikasjoner

Vitenskapelige artikler (NVI)

2018

A novel SRC-2-dependent regulation of epithelial-mesenchymal transition in breast cancer cells

Olivera Bozickovic, Linn Skartveit, Agnete Svendsen, Thomas Helland, Kristin Jonsdottir, Marianne Hauglid Flågeng, Ingvild Sveinsgjerd Fenne, Emiel Janssen, James Lorens, Lise Bjørkhaug, Jørn V. Sagen, Gunnar Mellgren
Journal of Steroid Biochemistry and Molecular Biology 185 p. 57-70
2016

Treatment with aromatase inhibitors stimulates the expression of epidermal growth factor receptor-1 and neuregulin 1 in ER positive/HER-2/neu non-amplified primary breast cancers

Marianne Hauglid Flågeng, Alexey Larionov, Jürgen Geisler, Stian Knappskog, Wenche S Prestvik, Geir Bjørkøy, Peer Kåre Lilleng, JM Dixon, William R. Miller, Per Eystein Lønning, Gunnar Mellgren
Journal of Steroid Biochemistry and Molecular Biology 165 p. 228-235
2015

The active tamoxifen metabolite endoxifen (4OHNDtam) strongly down-regulates cytokeratin 6 (CK6) in MCF-7 breast cancer cells

Thomas Helland, Jennifer Gjerde, Simon N Dankel, Ingvild Sveinsgjerd Fenne, Linn Skartveit, Andreas Drangevåg, Olivera Bozickovic, Marianne Hauglid Flågeng, Håvard Søiland, Gunnar Mellgren, Ernst Asbjørn Lien
PLOS ONE 10
2015

Estrogens correlate with PELP1 expression in ER positive breast cancer

Marianne Hauglid Flågeng, Stian Knappskog, Jennifer Gjerde, Per Eystein Lønning, Gunnar Mellgren
PLOS ONE 10:e0134351
2014

Estradiol determines the effects of PTH on ERα-dependent transcription in MC3T3-E1 cells

Monika Christensen, Ingvild Sveinsgjerd Fenne, Marianne Hauglid Flågeng, Bjørg Almås, Ernst Asbjørn Lien, Gunnar Mellgren
Biochemical and Biophysical Research Communications - BBRC 450 p. 360-365
2013

Downregulation of steroid receptor coactivator-2 modulates estrogen-responsive genes and stimulates proliferation of MCF-7 breast cancer cells

Ingvild Sveinsgjerd Fenne, Thomas Helland, Marianne Hauglid Flågeng, Simon E Nitter Dankel, Gunnar Mellgren, Jørn V. Sagen
PLOS ONE 8
2013

Inverse regulation of EGFR/HER1 and HER2-4 in normal and malignant human breast tissue

Marianne Hauglid Flågeng, Stian Knappskog, Ben P. Haynes, Per Eystein Lønning, Gunnar Mellgren
PLOS ONE 8
2012

Steroid receptor coactivators, HER-2 and HER-3 expression is stimulated by tamoxifen treatment in DMBA-induced breast cancer

Line Leonore Haugan Moi, Marianne Hauglid Flågeng, Jennifer Gjerde, Andre Greger Madsen, Therese Halvorsen Røst, Oddrun Anita Gudbrandsen, Ernst Asbjørn Lien, Gunnar Mellgren
BMC Cancer 12
2010

Effect of low-dose tamoxifen on steroid receptor coactivator 3/amplified in breast cancer 1 in normal and malignant human breast tissue

Line Leonore Haugan Moi, Marianne Hauglid Flågeng, Sara Gandini, Aliana Guerrieri-Gonzaga, Bernardo Bonanni, Matteo Lazzeroni, Jennifer Gjerde, Ernst Asbjørn Lien, Andrea De Censi, Gunnar Mellgren
Clinical Cancer Research 16 p. 2176-2186
2010

cAMP-mediated regulation of HNF-4 alpha depends on the level of coactivator PGC-1 alpha

Simon E Nitter Dankel, Tuyen Hoang, Marianne Hauglid Flågeng, Jørn V. Sagen, Gunnar Mellgren
BBA - Molecular Cell Research 1803 p. 1013-1019
2009

Nuclear receptor co-activators and HER-2/neu are upregulated in breast cancer patients during neo-adjuvant treatment with aromatase inhibitors

MH Flageng, Marianne Hauglid, Line Leonore Haugan Moi, J. Michael Dixon, Jurgen Geisler, Ernst Asbjørn Lien, William Russell Miller, PE Lonning, Per Eystein Lønning, Gunnar Mellgren
British Journal of Cancer 101 p. 1253-1260
2008

Recruitment of coactivator glucocorticoid receptor interacting protein 1 to an estrogen receptor transcription complex is regulated by the 3',5'-cyclic adenosine 5'-monophosphate-dependent protein kinase

Ingvild Sveinsgjerd Fenne, Tuyen Hoang, Marianne Hauglid, Jørn V. Sagen, Ernst Asbjørn Lien, Gunnar Mellgren
Endocrinology 149 p. 4336-4345
2008

Effects of CYP2D6 and SULT1A1 genotypes including SULT1A1 gene copy number on tamoxifen metabolism

Jennifer Fernandez Gjerde, Marianne Hauglid, M Hauglid, Harald Breilid, S. Lundgren, Jan Erik Varhaug, Elton Richard Kisanga, Gunnar Mellgren, Vidar Martin Steen, Ernst Asbjørn Lien
Annals of Oncology 19 p. 56-61
2005

Identification and quantification of tamoxifen and four metabolites in serum by liquid chromatography-tandem mass spectrometry

Jennifer Fernandez Gjerde, Elton Richard Kisanga, Marianne Hauglid, Pål Ivar Holm, Gunnar Mellgren, Ernst Asbjørn Lien
Journal of Chromatography A 1082 p. 6-14

Poster

2014

Steroid receptor coactivators during short-term estrogen deprivation

Marianne Hauglid Flågeng, Olivera Bozickovic, Linn Skartveit, Jørn V. Sagen, Gunnar Mellgren
2012

Inverse regulation of Neuregulin 1 and HER-3 during treatment with aromatase inhibitors of estrogen receptor-positive breast cancer

Marianne Hauglid Flågeng, Alexey Larionov, Jürgen Geisler, JM Dixon, Per Eystein Lønning, Gunnar Mellgren
2011

The nuclear receptor coactivator PELP1/MNAR is positively correlated with estrogen levels in breast cancer patients

Marianne Hauglid Flågeng, Stian Knappskog, Per Eystein Lønning, Gunnar Mellgren
2011

Characterization of Global Gene Expression in Breast Cancer Cells after cAMP/PKA-mediated downregulation of Steroid Receptor Coactivator 2

Ingvild Sveinsgjerd Fenne, Marianne Hauglid Flågeng, Thomas Helland, Simon E Nitter Dankel, Gunnar Mellgren
2010

The influence of tamoxifen treatment on the expression levels of liver receptor homolog (LHR-1)

Jennifer Gjerde, Aliana Guerrieri-gonzaga, Marianne Hauglid Flågeng, Sara Gandini, Line Haugan Moi, Bernardo Bonanni, Debora Macis, Harriet Johansson, Andrea Decensi, Gunnar Mellgren, Ernst A. Lien
2010

Expression of Steroid Receptor Coactivators and HER-2/neu in normal and malignant breast tissue in controls and tamoxifen treated patients

Marianne Hauglid Flågeng, Line Leonore Haugan Moi, Sara Gandini, Aliana Guerrieri Gonzaga, Bernardo Bonanni, Matteo Lazzeroni, Jennifer Gjerde, Ernst Asbjørn Lien, Andrea Decensi, Gunnar Mellgren
2010

Epidermal growth factor receptors (ErbB/HER) and the ligand Neuregulin 1 (NRG1) increase in breast tumors during short time treatment with aromatase inhibitors

Marianne Hauglid Flågeng, Stian Knappskog, Alexey Larionov, Jurgen Geisler, Mike Dixon, William R. Miller, Per Eystein Lønning, Gunnar Mellgren
2009

PTH inhibits ligand-dependent activation of estrogen receptor alfa in MC3T3 osteoblasts

Monika Christensen, Ingvild Sveinsgjerd Fenne, Marianne Hauglid Flågeng, Bjørg Almås, Ernst Asbjørn Lien, Gunnar Mellgren
2009

HER-2/neu and nuclear receptor coactivators are upregulated in breast cancer tumors during estrogen deprivation

Marianne Hauglid Flågeng, Line Leonore Haugan Moi, J. Michael Dixon, Jürgen Geisler, Ernst Asbjørn Lien, William R. Miller, Per Eystein Lønning, Gunnar Mellgren
2009

PTH inhibits ligand-dependent activation of estrogen receptor alfa in MC3T3 Osteoblasts

Monika Christensen, Ingvild Sveinsgjerd Fenne, Marianne Hauglid Flågeng, Bjørg Almås, Ernst Asbjørn Lien, Gunnar Mellgren
2009

Role of the cAMP-PKA Signaling Pathway in the Regulation of ERalpha-dependent transcription by Steroid Receptor Coactivators in Breast Cancer Cells

Ingvild Sveinsgjerd Fenne, Marianne Hauglid Flågeng, Tuyen Hoang, Gunnar Mellgren
2008

Changes in mRNA expression levels of steroid receptor coactivators correlate with treatment response to aromatase inhibition in human breast cancer

Marianne Hauglid, Line Leonore Haugan Moi, Michael Dixon, Jurgen Geisler, William R. Miller, Ernst Asbjørn Lien, Per Eystein Lønning, Gunnar Mellgren
2007

Effect of CYP2D6 and SULT1A1 Genotypes on the serum concentration of 4-OHtamoxifen and 4-OH-N-Demethyltamoxifen during steady state treatment of breast cancer patients

Jennifer Fernandez Gjerde, Marianne Hauglid, Harald Breilid, Steinar Lundgren, Elton Richard Kisanga, Gunnar Mellgren, Vidar Martin Steen, Ernst Asbjørn Lien

Kapitler og bøker

2011

Steroid Receptor Coactivators and Their Expression, Regulation and Functional Role in Endocrine Responsive and Resistant Breast Cancer

Line Leonore Haugan Moi, Marianne Hauglid Flågeng, Ingvild Sveinsgjerd Fenne, Jennifer Gjerde, Ernst Asbjørn Lien, Gunnar Mellgren
p. 715-732
2011

Steroid Receptor Coactivators and Endocrine Treatment in Breast Cancer

Line Leonore Haugan Moi, Marianne Hauglid Flågeng, Simon E Nitter Dankel, Tuyen Hoang, Jennifer Gjerde, Jørn V. Sagen, Ernst Asbjørn Lien, Gunnar Mellgren
p. 35-66

Populærvitenskapelige artikler

2013

Steroid reseptor koaktivatorer, HER-2 og hormonbehandling ved brystkreft

Line Leonore Haugan Moi, Marianne Hauglid Flågeng, Gunnar Mellgren
Bestpractice : dialog mellom leger p. 8-13

Annet tidsskriftbidrag

2008

A study of associations between estrogen and tamoxifen metabolism, cytochrome 2D6 and sulfotransferase 1A1 polymorphisms, and sulfotransferase 1A1 gene copy number during steady state tamoxifen treatment

Jennifer Fernandez Gjerde, Jurgen Geisler, Steinar Lundgren, Dagfinn Ekse, Harald Breilid, Marianne Hauglid, M Hauglid, EJ Varhaug, Jan Erik Varhaug, Vidar Martin Steen, Per Eystein Lønning, PE Lonning, Ernst Asbjørn Lien
Breast Cancer Research and Treatment 109 p. 592-592
2007

Effect of CYP2D6 and SULT1A1 genotypes on the serum concentration of 4-hydroxytamoxifen and 4-hydroxy-N-demethyltamoxifen during steady state treatment of breast cancer patients

Jennifer Fernandez Gjerde, Marianne Hauglid, Harald Breilid, Steinar Lundgren, Jan Erik Varhaug, Elton Richard Kisanga, Gunnar Mellgren, Vidar Martin Steen, Ernst Asbjørn Lien
Breast 16 p. S15-S15
2007

A study of associations between estrogen and tamoxifen metabolism, cytochrome 2D6 and sulfotransferase 1A1 polymorphisms, and sulfotransferase 1A1 gene copy number during steady state tamoxifen treatment

Jennifer Fernandez Gjerde, Jurgen Geisler, Steinar Lundgren, Dagfinn Ekse, Harald Breilid, Marianne Hauglid, Jan Erik Varhaug, Gunnar Mellgren, Vidar Martin Steen, Per Eystein Lønning, Ernst Asbjørn Lien
Breast Cancer Research and Treatment S106
2005

Relationship between CYP2D6 and SULT1A1 genotypes and serum concentrations of tamoxifen and its metabolites during steady state treatment in breast cancer patients

Jennifer Fernandez Gjerde, Marianne Hauglid, Harald Breilid, Steinar Lundgren, Jan Erik Varhaug, Elton Richard Kisanga, Gunnar Mellgren, Vidar Martin Steen, Ernst Asbjørn Lien
Breast Cancer Research and Treatment 94 p. S236-S237

Rapporter og avhandlinger

2011

Steroid receptor coactivators and epidermal growth factor receptors in breast cancer

Flågeng, Marianne Hauglid
2010

Endring i genekspresjon under endokrin behandling av brystkreft

Ingebjørg Johnsen Hjetland, Marianne Hauglid Flågeng
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